HSB

HSB may refer to:
 * HSB (Sweden), a cooperative housing association
 * HSB color space
 * HSB Televisión, a Colombian television station
 * Bremen University of Applied Sciences (German: Hochschule Bremen)
 * Hang Seng Bank, a bank based in Hong Kong
 * Hardly Strictly Bluegrass, a music festival in San Francisco, California, United States
 * Hartford Steam Boiler Inspection and Insurance Company, an American equipment breakdown insurer
 * Harz Narrow Gauge Railways (German: Harzer Schmalspurbahnen), a steam railway in Germany
 * Erivan K. Haub School of Business, at Saint Joseph's University in Philadelphia, Pennsylvania, United States
 * "Heart-Shaped Box", a Nirvana song
 * Heaven Shall Burn, a German extreme metal band
 * Helensburgh railway station, in Australia
 * Helgeland Sparebank, a Norwegian bank
 * Helsby railway station, in England
 * Hill Street Blues, a serial police drama
 * Humidity Sounder for Brazil, an instrument on the Aqua satellite
 * Hunter-Schreger band, a feature of the tooth enamel in mammals
 * Upper Sorbian language (ISO 639-2 language code)
 * Head Start Bureau, a United States federal government agency which runs the Head Start program